RNA Details
Disease Name
liver cirrhosis
Tissue
liver
RNA Symbol
mir-30c-2
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
rattus norvegicus
Detection Methods
dual-lucimmunofluorescenceerase reporter assay; PCR;
Target
PAI-1
Pathway
NA
PubMed ID
Title
Involvement of miR-30c in hepatic stellate cell activation through the repression of plasminogen activator inhibitor-1
Year
2016
Function
"Microrna-30a is involved in the activation of hepatic stellate cells by inhibiting plasminogen activator inhibitor-1, and can be used as biomarkers of hepatic fibrosis ; Cirrhosis. Ang ii stimulation can reduce the expression of mir-30a."